5,819 research outputs found

    More experiments may help explore what works in conservation

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    The following article is republished from The Conversation, dated 6 November 2018. The article has not been edited, but we have attributed the author and her institute, given the internet citations, and used a non-copyrighted illustration

    Building a Cohesive Classroom: The effects of music on cooperation and community in a public, lower elementary, Montessori classroom

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    The following research assesses how the daily integration of singing and listening to music helps to construct a socially cohesive, cooperative and joyful classroom during clean up time. This study combined group singing opportunities, a music listening station and music played during clean up time. The songs used for this study included lyrical themes of cooperation, happiness, overcoming obstacles and/or friendship. The thirty-day study involved twenty-one participants between the ages of six and nine at a public, Montessori school in Missouri. Each individual completed a pre- and post-survey, as well as a survey each time they used the music listening station. During clean up time, observations were taken daily to record instances of helpful behaviors and joy amongst the participants. Results of the surveys showed that the intervention was successful at increasing positive experiences during clean up time and including a Music Listening Station as an available work choice. The intervention was not successful in creating positive experiences when singing together as a group. Further research may include the use of other mediums to promote community and collaboration like the fine arts, sports or other group oriented activities

    State Intervention in Pregnancy

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    Insight into Translational Activation in Yeast Mitochondria

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    Mitochondrial function depends on over a thousand proteins, of which the majority are nuclear DNA-encoded and approximately one percent are mitochondrial DNA-encoded. The mitochondrial DNA of Saccharomyces cerevisiae contains eight protein-encoding genes, seven of which are required for proper function of the respiratory complexes and one encodes a ribosomal protein. The bigenomic nature of the oxidative phosphorylation complexes requires coordinated expression and regulation from both the nuclear and the mitochondrial genomes. It is currently unclear how this regulatory network operates. However, it is thought that nuclear genome-encoded messengers localized to the mitochondria aid in this coordination. A family of proteins termed mitochondrial translational activators has been shown to control the expression of all mitochondrial-encoded protein genes in a gene-specific manner. Evidently, each mitochondrial mRNA is regulated by a specific protein or a subset of proteins that permits translation of that transcript. If these factors are absent, there will be no synthesis of the polypeptide, leading to a respiratory deficient cell. Although a functional link between translational activators and the mitochondrial genes they control has long been established genetically, the activation mechanism is entirely unknown. This study focuses on the mechanism of activation of two representative members of this translational activator family, Pet111p and Cbp1p. These activators are required for the expression of COX2 and COB, respectively. Translational activators have been shown to have multiple functions including, transcript stabilization and mRNA localization to the membrane, as well as to the translation machinery. Current genetic data suggests that both Pet111p and Cbp1p interact with RNA targets in the 5′-untranslated regions of COX2 and COB, respectively. However, neither the identity of these sites, nor has the ability of these proteins to interact with RNA ever been demonstrated. The objective of this study is to characterize the functional mechanism of translational activation for both Pet111p and Cbp1p and ultimately learn how they aid in the coordination of dual-genomic expression

    The Usefulness of Neutrality

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    Recently, the idea of therapeutic neutrality has been attacked. Many observers have suggested that the neutral therapist is inhuman and unempathic. Actually, being a neutral therapist means being especially human and empathic. The neutral therapist\u27s empathic contact with the patient is the most extensive in that it includes not only contact with feelings and thoughts of which the patient is aware, but also contact with all those intolerable thoughts and feelings of which the patient prefers to be unaware. Such awareness in the therapist is possible only when the therapist remains, as Anna Freud (I) recommends, equidistant from the patient\u27s id, ego and superego, that is equidistant from the forces generating the patient\u27s psychic conflict. Such objectivity does not preclude warmth, rather it directly evolves from warm and authentic contact with the patient

    Library by Day, Theater by Night

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    This project will re-conceive a historic movie theater, honoring the program of the building as it was originally intended, while introducing a new programmatic element: the library. Instead of this large space only being used in the evenings for movie showings, it will now also be a place for the public to gather during the day as a popular materials library. This project is an exploration of diversion through literature and cinema. This space will continue to be a landmark in Richmond and a place community members visit on a regular basis. How do new elements introduced into a historic building respond to the existing ornamentation? How do two different programs meet one another and share a space? What makes for a successful and honorable adaptive reuse of a building? Why is diversion important? The methods used for this project were to study large scale, recently constructed library projects like the Helsinki Central Library Oodi to understand the world’s latest and best strategies in library design programmatically and architecturally. This project is not on the same scale as these institutions, so a study of recent award-winning branch libraries was relevant as well. An interview was conducted with local designer, Shannon Wray, who was on the team that recently completed two such branch libraries in Central Virginia. Precedent studies were conducted of movie theaters and libraries throughout history. At new libraries like the Oodi in Helsinki, at least half of the square footage of the library building is no longer dedicated to books and instead dedicated to meeting spaces, maker spaces, art galleries, space for pop up markets, theaters, and play space (Tucker, 2019). The library building itself is an architectural attraction that brings in locals and tourists alike (Krueger, 2019). Reading a book and watching a movie are diversions. A library focused purely on entertainment will be better utilized than a traditional library. A better utilized civic space will lead to greater education, interaction between cultures, community engagement and economic well-being in the community

    Regional Working in the East of England: Using the UK National Standards for Public Involvement

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    Plain English summary: Involving patients and members of the public to help shape and carry out research is recommended in health research in the United Kingdom (UK). There are a number of regional networks of Patient and Public Involvement (PPI) groups, which support the collaboration between researchers, patients and public members. We are a group of researchers, patients and public members who came together via a PPI regional network in the East of England to collaborate on a research study about the extent of feedback from researchers to PPI contributors.The aim of this paper is to use the recently developed UK National Standards for Public Involvement to structure our thinking about what worked well and what did not, within our recently completed study. We believe this paper is one of the first to use the National Standards to structure a retrospective reflection on PPI within a study.Our findings showed that there are benefits of regional working, including easier access to public members and bringing together researchers, public members and those who run PPI groups for research collaboration. The main challenges included involvement of people before studies are funded and working across organisations with different payment processes.The National Standards for Public Involvement has provided a useful framework to consider how best to involve patients and members of the public in research and could be a helpful structure to reflect on successes and challenges in individual projects and also regional, national or international comparisons of PPI in research. Abstract: Background Regional networks of Patient and Public Involvement (PPI) organisations, including academic institutions, health and social care services, charities, patient and public groups and individuals, can play an important part in carrying out health research. In the UK, recommendations by the National Institute of Health Research (NIHR) encourage the use of regional, collaborative networks with shared resources and training. Methods The newly developed UK National Standards for Public Involvement were used as a framework for a retrospective reflection of PPI within a recently completed research study which focused on feedback from researchers to PPI contributors. PPI contributors, those running PPI groups (PPI leads) and researchers involved in the study have contributed to this reflection by completing evaluation forms throughout the research alongside notes of meetings and co-authors' final reflections. Results Results revealed a number of successes where the regional network was particularly useful in bringing together PPI contributors, those who lead PPI groups and researchers. The regional network helped researchers to get in touch with patients and members of the public. Challenges included involving people before funding and bureaucratic and financial barriers when working across different organisations in the region. The importance of working together in flexible, informal ways was key and on-going support for the PPI contributors was vital for continued involvement, including emotional support not just monetary. The first four National Standards of inclusive opportunities, working together, support and learning and communications were particularly useful as means of structuring our reflections. Conclusions To our knowledge, this is one of the first research studies to use the UK National Standards for Public Involvement as a framework to identify what worked well and the challenges of PPI processes. It is suggested that as more reflective papers are published and the National Standards are more widely used in the UK, many lessons can be learnt and shared on how to improve our Patient and Public Involvement within research studies. Evaluations or reflections such as these can further enhance our understanding of PPI with implications for regional, national and international comparisons.Peer reviewedFinal Published versio
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